Experimental TB drug explodes bacteria from the inside out

An international team of biochemists has discovered how an experimental drug unleashes its destructive force inside the bacteria that cause tuberculosis (TB).

Major North American breakthrough for dialysis patients

Suffering from end-stage renal disease (ESRD), a growing number of patients at the Centre hospitalier de l’Université de Montréal (CHUM), have become the beneficiaries of a North American breakthrough: high efficacy hemodiafiltration (HDF).

Master gene plays key role in blood sugar levels

When mice that lack steroid receptor-2 (SRC-2) – a master regulator gene called a coactivator – fast for a day, their blood sugar levels plummet.

Selenium may slow march of AIDS

(Penn State) Increasing the production of naturally occurring proteins that contain selenium in human blood cells slows down multiplication of the AIDS virus, according to biochemists.

Ceregene announces data from phase 2 clinical trial of CERE-120 for Parkinson’s

Ceregene, Inc., a biopharmaceutical company, today reported clinical data from a double-blind, controlled Phase 2 trial of CERE-120 in 58 patients with advanced Parkinson’s disease.

FDA issues complete response letter for Ceftobiprole for treatment of complicated skin infections

Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD), today announced that it received a Complete Response letter from the U.S. Food and Drug Administration (FDA) regarding its New Drug Application (NDA) for ceftobiprole for the treatment of complicated skin and skin structure infections, including diabetic foot infections.

Misleading media coverage of clinical trials

Media coverage of clinical trials does not contain the elements readers require to make informed decisions.

First study showing how protein fine-tunes the heart

Dr Andrew Whitten, Dr Cy Jeffries and Professor Jill Trewhella, from the School of Molecular and Microbial Biosciences, University of Sydney, with Samantha Harris, from the University of California, USA, have the first data showing how a protein in heart muscle cells works to maintain regular heart function.

Defective calcium metabolism in nerve cells contributes to neurological disorder

Defective calcium metabolism in nerve cells may play a major role in a fatal genetic neurological disorder that resembles Huntington’s disease, researchers at UT Southwestern Medical Center have found in a mouse study.

Progress in cancer fight, but Congress, States must step up efforts to reduce smoking, lung cancer

Delivering good news for our nation’s health, a new report released by the nation’s leading cancer organizations finds that, for the first time, both the incidence and death rates for all cancers combined are decreasing for both men and women, driven in part by declines in smoking and lung cancer.