Chronic infection may add to developing-world deaths

(Massachusetts Institute of Technology) Worldwide, nearly 2 million people per year die from diarrhea, the vast majority of them in poor countries. The disease accounts for 18 percent of all deaths among children — and yet is almost always preventable with proper treatment. Now, MIT research indicates that underlying, low-level undiagnosed infection may greatly add [...]

Next gen sequencing technology pinpoint ‘on-off switches’ in genomes

(DOE/Joint Genome Institute) Scientists from the US Department of Energy Joint Genome Institute and Berkeley Lab have developed a set of molecular tools that provide important insight into the complex genomes of multicellular organisms. The strategy promises to clarify the longstanding mystery of the role played by vast stretches of DNA sequence that do [...]

Stem cell research uncovers mechanism for type 2 diabetes

(Burnham Institute) Taking clues from their stem cell research, investigators at the University of California San Diego and Burnham Institute for Medical Research have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 diabetes.

New Fulbright Scholars focus on rural development in Nepal, risk communication in Thailand

(Worcester Polytechnic Institute) Two faculty members from Worcester Polytechnic Institute are at work in Asia as Fulbright Senior Scholars. Thomas B. Robertson, assistant professor of history, is exploring the consequences of American rural development in Nepal. Seth P. Tuler, research assistant professor of interdisciplinary and global studies, is looking at the need for improved environmental [...]

Fructose-sweetened drinks increase nonfasting triglycerides in obese adults

(Monell Chemical Senses Center) Obese people who drink fructose-sweetened beverages with their meals have an increased rise of triglycerides following the meal, according to new research from the Monell Center. This effect was especially pronounced in insulin-resistant subjects, worsening their already adverse metabolic profiles and potentially increasing their risk for heart disease and other metabolic [...]

Treating asthma with NIOX MINO offers cost savings for the UK health care system

(Aerocrine) Aerocrine AB has reported the recent publication of a UK study evaluating the effect of routine inflammation measurement in asthma.The economic study was intended to evaluate the effect on the direct costs of UK asthma care when buying and using Aerocrine’s NIOX MINO product.

Study on ustekinumab for treatment of psoriatic arthritis published

A group of patients suffering from potentially debilitating psoriatic arthritis showed significant and prolonged improvement after treatment with ustekinumab, according to data from a randomized, double-blind, placebo-controlled study in patients with moderate to severe psoriatic arthritis (PsA).

Candesartan cilexetil reduces proteinuria in kidney disease patients

Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology ( JASN ).

Compound can distinguish between benign tissue and localized and metastatic prostate cancer

Researchers have determined that a molecule produced by the bodys metabolism could be used to differentiate between benign prostate tissue vs. localized and metastatic prostate cancer.

Volcanoes in the genome, blowing out pieces of DNA

Roughly 10 million years ago, a major genetic change occurred in a common ancestor of gorillas, chimpanzees, and humans.