Clostridium difficile Infection in Primary Care: Tackling a Virulent Pathogen

Review treatment options for patients with new onset, severe, and recurrent C difficile infection.

Lawmakers Introduce Bill to Improve Emergency Care

WASHINGTON (MedPage Today) — Sen. Debbie Stabenow (D-Mich.) introduced a bi-partisan bill this week to give emergency physicians a pay boost and establish a committee to find fixes for overcrowded emergency rooms.

Negative Data on Seroquel Allegedly Suppressed by Drugmaker

ORLANDO (MedPage Today) — Newly unsealed court documents suggest that AstraZeneca tried to minimize the risk of diabetes and weight gain associated with its antipsychotic drug quetiapine (Seroquel), in part by “cherry-picking” data for publication.

Opioid Abuse and Dependence in the Chronic Pain Patient: Interventions to Decrease Risk and Improve Outcomes

Review the challenges of treating a patient with chronic pain and with a history of substance abuse and evaluate interventions that are available or are in development.

Debate Continues Over Blood Donation From Men Who Have Sex With Men

Although some developed countries now accept blood donations from men who have ever had sex with men, most do not; the debate about this practice is ongoing. Medscape Medical News

Exacerbations of COPD May Cluster Together in Time

Exacerbations of chronic obstructive pulmonary disease clustered together after an initial exacerbation, which may affect timing of preventative interventions and clinical trial data analysis. Medscape Medical News

Pre-Exposure Prophylactic Regimen Could Cut the Risk of HIV Transmission

A pre-exposure prophylactic (PrEP) regimen of tenofovir and emtricitabine has the potential to reduce the lifetime risk of HIV transmission substantially in high-risk populations, a new study indicates. Reuters Health Information

Calcium Intake May Protect Against Cancer

A prospective study shows a lower risk for cancer overall in women with higher intake of calcium and a lower risk for gastrointestinal tract cancers in both men and women with high calcium intakes. Medscape Medical News

Warning of Tardive Dyskinesia Risk Strengthened for Metoclopramide

ROCKVILLE, Md. (MedPage Today) — Drugs containing the antiemetic metoclopramide must carry a boxed warning about the risk of tardive dyskinesia, the FDA announced.

WHO Approves Heat-Stable, Generic Version Of Abbott’s Kaletra

The pharmaceutical company Mylan on Wednesday announced that the World Health Organization has approved its heat-stable, generic version of Abbott Laboratories’ antiretroviral drug Kaletra, the AP/MSNBC reports.