Report Describes Origins of Influenza A (1 H1N1) Virus

Genes included in the novel influenza A (H1N1) genome have been circulating undetected for an extended period, according to an analysis published today in Science. Medscape Medical News

Intensive Glucose Control Reduces MI and CHD-Event Risk, New Meta-Analysis Shows

The findings, which include five of the pivotal diabetes studies that have caused a stir regarding glucose control, support continued therapy that lowers elevated glycated hemoglobin A1c to less than 7.0%, say researchers. Heartwire

Give Blood Pressure Drugs to All

Law and Wald, the duo that brought us the polypill, now urge that everyone “over a certain age” be put on antihypertensive medication to lower their blood pressure, even if it’s normal, to ward off cardiovascular disease and stroke. Heartwire

MADIT-2 at 8 Years: Further ICD Survival Gains, Signs of Improved Cost-Effectiveness

Mortality continued to drop in patients with primary-prevention defibrillators, even after they showed a significant survival benefit out to four years, suggests a post hoc analysis of the seminal trial. Heartwire

Neurology Research Round-up: The Best of AAN 2009

Important studies presented include cladribine, fingolimod, and pulsed oral steroids for multiple sclerosis; mitoxantrone for MS increases leukemia risk more than previously thought; a study of traumatic brain injury in veterans; reassuring news about pregnancy in epilepsy; and an analysis of SPARCL trial results showing the more stroke risk-factor reductions, the better. Medscape [...]

WHO to Revise Definition of Global Pandemic

The World Health Organization (WHO) is redefining the criteria for pandemic alert level phase 6, the final alert phase, indicating that a global pandemic of influenza A (H1N1) is under way. Medscape Medical News

FDA Wrapping Up Sunscreen Label Changes

The FDA will not allow claims of 50+ SPF, among other labeling changes, on sunscreens. WebMD Health News

USPSTF Recommends Syphilis Screening for All Pregnant Women

The US Preventive Services Task Force has reaffirmed its recommendation to screen all pregnant women for syphilis infection. Medscape Medical News

Ischemic Symptoms Linked to Increased Cardiovascular Risk in Women

Women with symptoms and signs suggesting ischemia but without findings of obstructive coronary artery disease are at elevated risk for cardiovascular events vs asymptomatic community-based women. Medscape Medical News

Chlamydia May Have Etiologic Role in Undifferentiated Spondylarthritis

A new study suggests that chlamydial infection, which is often occult, may be a cause of undifferentiated spondylarthritis (uSpA) in many patients. Reuters Health Information