Polymorphisms Of The Interleukin-1 Gene Complex May Influence Alcohol Dependence

Cytokines are small proteins secreted by cells that serve as molecular messengers between cells. Pro-inflammatory cytokines - which function in the immune system- may be involved in dependence (AD). A study of three polymorphisms of the interleukin-1 complex (IL-1) and one of the necrosis factor-alpha (TNFα) has found that IL-1 may directly contribute to AD among Spanish Caucasian males.


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