Obama Declares H1N1 a National Emergency

WASHINGTON (MedPage Today) — President Obama has upped the ante in the battle to control the H1N1 flu by declaring it a national emergency, the second such declaration since the flu first emerged last spring.

Week 19: No SGR Fix Before Reform, More Talk of a Public Plan

WASHINGTON (MedPage Today) — After a procedural vote on Wednesday made it clear that a bill to reform Medicare’s physician payment system won’t pass any time soon, focus shifted back to the healthcare reform bills in the House and the Senate — and to a public plan option.

PML Found in Patient on Rituximab Monotherapy

A case of progressive multifocal leukoencephalopathy has been reported in a rheumatoid arthritis patient taking rituximab (Rituxan) who had not previously received anti-tumor necrosis factor therapy, according to the drug’s manufacturer.

CHMP grants positive opinion to extend the use of Angiox to patients undergoing PCI

The Medicines Company announced today that the Committee for Medicinal Products for Human Use (CHMP) has granted a positive opinion applicable to all Member States of the European Union/European Economic Area that will extend the use of Angiox (bivalirudin) to include patients with heart attacks (so-called ST segment elevation myocardial infarction (STEMI)) undergoing emergency heart [...]

Updated data on XL184 study in patients with glioblastoma multiforme presented

Exelixis, Inc. and Bristol-Myers Squibb Company today reported updated phase 2 clinical data which show that XL184 demonstrated activity in patients with glioblastoma multiforme (GBM), the most common and aggressive form of brain cancer.

TransMolecular announces final results from its Phase 2 clinical study of 131I-TM601

TransMolecular, Inc., a developer of innovative oncology drugs through targeted delivery technologies, today announced final results from its Phase 2 clinical study comparing the toxicity and overall survival of three versus six intracavitary injections of its anti-cancer compound 131I-TM601 in the treatment of recurrent malignant glioma.

Bayer And Onyx Initiate Phase 3 Trial Of Nexavar In Patients With Non-Responsive Thyroid Cancer

Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) announced the companies have begun enrolling patients in an international Phase 3 trial to evaluate Nexavar® (sorafenib) tablets for the treatment of patients with radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer. This Phase 3 trial was started based on the results from [...]

Protein Purification Challenge Could Be Solved By Biochemical ‘On-Switch’

Drugs based on engineered proteins represent a new frontier for pharmaceutical makers. Even after they discover a protein that may form the basis of the next wonder drug, however, they have to confront a long-standing problem: how to produce large quantities of the protein in a highly pure state.

ULURU presents clinical posters; highlights efficacy of Altrazeal dressing for wound care

ULURU Inc. (NYSE Alternext: ULU) today announced that Gregory Bohn, M.D., FACS, Medical Director, Trinity Wound Care and Hyperbaric Medicine, Bettendorf, Iowa, has presented nine clinical posters at the 24th Annual “Clinical Symposium on Advances in Skin and Wound Care” being held in San Antonio, Texas.

Lpath to present clinical results of iSONEP drug in wet-AMD patients

Lpath, Inc. (OTCBB: LPTN), the category leader in therapeutic agents against bioactive lipids, will present at the 2009 BIOCOM Investor Conference, which will be held October 26-27, 2009 at the Hyatt Regency La Jolla in San Diego, California.