Premature Adult Mortality Falls but Gender Gap Widens

Although worldwide adult mortality rates have been dropping overall for the past four decades, the gap between men and women, who have lower mortality risk, has widened, researchers found.

J&J Settles Topamax Marketing Case for $81 Million

Johnson & Johnson has agreed to pay $81 million to settle charges that it improperly marketed its epilepsy drug topiramate (Topamax).

Deadline Looms for States on New High-Risk Pools

WASHINGTON (MedPage Today) — States have until the end of day Friday to inform the Department of Health and Human Services whether they want to run their own temporary high-risk insurance pools established by the new healthcare reform law, or whether they want the federal government to do it for them.

ICU Care Less Intense, Outcome Worse for Uninsured (CME/CE)

Critically ill patients who have no health insurance are less likely to be admitted to a hospital, receive fewer critical care services, and are more likely to die, an official review from the American Thoracic Society affirmed.

SGIM: Surgery Among Minorities Increases as Insurance Expands (CME/CE)

MINNEAPOLIS (MedPage Today) — Healthcare reform in Massachusetts appears to have increased the number of minorities receiving some surgical procedures, researchers say.

FDA Approves Prostate Cancer Vaccine

WASHINGTON (MedPage Today) — The FDA today approved the immunotherapeutic agent sipuleucel-T (Provenge) for the treatment of advanced prostate cancer, almost three years after the agency rejected an advisory group’s approval recommendation for the drug.

Lotus Pharmaceuticals receives Chinese SFDA approval to commence Laevo-Bambuterol clinical trials

Lotus Pharmaceuticals, Inc., a growing developer, manufacturer and seller of medicine and drugs in the People’s Republic of China today reported that its innovative asthma drug Laevo-Bambuterol has received approval from China’s State Food & Drug Administration’s (SFDA) to commence clinical trials (No.2010L01309 and 2010L01399).

EnzymeRx reports positive results from first clinical trial of pegsitacase for refractory gout

EnzymeRx, LLC, a clinical-stage biotechnology company, today announced top line results from its first clinical trial of pegsitacase (formerly called Uricase‑PEG 20). Pegsitacase is a pegylated uricase being developed by EnzymeRx for the treatment of refractory gout and for the management of hyperuricemia associated with tumor lysis syndrome.

Kissei to commercialize Protox’s PRX302 PSA-activated pro-drug for BPH, prostate cancer in Japan

Protox Therapeutics Inc., a leader in the development of receptor targeted fusion proteins, today announced that it has entered into an exclusive US $75 million license agreement with Kissei Pharmaceutical Co., Ltd. for the development and commercialization of its PSA-activated pro-drug, PRX302, in Japan for BPH, prostate cancer and other diseases of the prostate. Protox [...]

Artisan Pharma enrolls 750 patients in Phase 2b study of ART-123 in sepsis patients with DIC

Artisan Pharma, Inc., a private biopharmaceutical company dedicated to bringing best-in-class critical care therapeutics to patients, today announced the completion of patient enrollment in its Phase 2b study of ART-123 (Recomodulin® - recombinant human thrombomodulin) in sepsis patients with disseminated intravascular coagulation (DIC). The clinical trial was a randomized, double-blind, placebo-controlled Phase 2b study to [...]