New clues to molecular action of Alzheimer’s drug memantine

Alzheimer’s disease destroys cells and their connections (called synapses), causing memory loss and other cognitive problems that disrupt work, hobbies and daily life. Symptoms can be alleviated, in part, by the memantine (marketed in the United States as Namenda), which is currently FDA-approved to treat moderate-to-severe Alzheimer’s disease and was, in part, developed by Stuart A. Lipton, M.D., Ph.D., Director of the Del E. Web Center for Neuroscience, Aging and Stem Cell Research at Sanford-Burnham Medical Research Institute (Sanford-Burnham).


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