To Reduce HIV Risk Among Men Who Have Sex With Men, Better Interventions Are Needed

Although a cognitive-behavioral intervention to encourage men who have sex with men to reduce their substance use and sexual risk behavior (as both are linked) was partially successful, a similar reduction was achieved in comparison groups who did not receive the intervention suggesting that better methods for changing behaviors are needed…

Molecular Approaches To Better Understand Male Infertility

Male infertility is a common medical problem, affecting millions of men in the United States annually. Its causes include an inability to make productive sperm. Now, using yeast as a model organism, researchers at the University of Pennsylvania School of Medicine are beginning to identify the molecular signals that could in part underlie that problem. [...]

Car Crash Injury Costs Yield Sticker Shock

(MedPage Today) — Medical expenses and costs of lost productivity related to motor vehicle crashes topped $99 billion dollars in a single year, according to CDC investigators.

Medicare to Cover Smoking Cessation

WASHINGTON (MedPage Today) — Good news for seniors who want to quit smoking — Medicare will now cover tobacco cessation counseling — the Department of Health and Human Services announced.

Novel Combo Pill for Hypertension Approved

(MedPage Today) — Another type of combination pill for hypertension has won FDA approval — this time putting a direct renin inhibitor together with a calcium channel blocker.

Huber Needles Recalled

WASHINGTON (MedPage Today) — The FDA has issued a class I recall, the agency’s most serious, for Huber needles that were found to produce cores — slivers of silicone — when they penetrate a vascular access port.

Merck’s initiation of IMO-2055 Phase 1b clinical trial in SCCHN triggers €3.0M milestone payment to Idera

Idera Pharmaceuticals, Inc., today announced that it has achieved a milestone under its worldwide licensing and collaboration agreement with Merck KGaA, Darmstadt, Germany. The milestone was achieved upon Merck KGaA’s initiation of a Phase 1b clinical trial of IMO-2055 (EMD 1201081), an agonist of Toll-like Receptor 9 (TLR9), in combination with cisplatin, fluorouracil and cetuximab [...]

Experimental drug PLX4032 holds promise against cancers with faulty BRAF gene

An experimental drug designed to treat cancers with a particular genetic fault has shown promising results in a small clinical trial.

FDA denies accelerated approval of Genentech’s trastuzumab-DM1 (T-DM1) BLA for metastatic breast cancer

In its review of the BLA, the FDA stated the T-DM1 trials did not meet the standard for accelerated approval because all available treatment choices approved for metastatic breast cancer, regardless of HER2 status, had not been exhausted in the study population.

Vanda Pharmaceuticals initiates tasimelteon Phase III clinical trial for Non-24-Hour Sleep Wake Disorder

Vanda Pharmaceuticals Inc., today announced it has initiated a Phase III clinical trial to evaluate tasimelteon in patients with Non-24-Hour Sleep Wake Disorder (N24HSWD), a condition experienced primarily by totally blind individuals that results in abnormal night sleep patterns and chronic daytime sleepiness.