End of Life Hospice Care Rising Among HF Patients (CME/CE)

(MedPage Today) — Care at the end of life for heart failure patients has grown progressively more expensive — but with a shift toward greater use of hospice care, two studies from the U.S. and Canada have found.

First Patient in Pioneering ESC Trial

(MedPage Today) — The first clinical trial of a human embryonic stem cell (ESC) therapy has enrolled its first patient, according to the company sponsoring the study.

Guatemala Study ‘Regrettable,’ Say CDC and NIH Heads

(MedPage Today) — The directors of the CDC and the National Institutes of Health have condemned the U.S. government-funded study in the 1940s that deliberately infected dozens of Guatemalans with sexually transmitted diseases, calling it “regrettable and deeply saddening.”

FDA Turns Down Loxapine Inhaler for Agitation

(MedPage Today) — An inhaled version of the antipsychotic drug loxapine for treating agitation in patients with schizophrenia or bipolar disorder won’t be approved anytime soon.

Delayed-Release Form of Risedronate Approved

(MedPage Today) — A delayed-release formulation of the osteoporosis drug risedronate, which may be easier for some patients to take, has won FDA approval, its manufacturer announced.

USPTO issues Watson Notice of Allowance for key progesterone patent to treat or prevent preterm birth

Columbia Laboratories, Inc. announced today that the U.S. Patent and Trademark Office (USPTO) has issued Watson Pharmaceuticals, Inc. a Notice of Allowance for a key patent for the use of progesterone to treat or prevent preterm birth. The USPTO issues a Notice of Allowance to report that a patent application has been examined and is [...]

Alimera to present Iluvien Phase 3 clinical trial data at AAO annual meeting

Alimera Sciences, Inc., a biopharmaceutical company that specializes in the research, development and commercialization of prescription ophthalmic pharmaceuticals, today announced that data from its Phase 3 (FAME) clinical trials for Iluvien will be presented this month at the annual meeting of the American Academy of Ophthalmology (AAO) in Chicago.

First presentation of anti-HER2 antibody-drug conjugate as first-line therapy for advanced breast cancer

A new type of breast cancer treatment has shown encouraging activity as a first-line therapy in HER2-positive metastatic disease, researchers reported at the 35th Congress of the European Society for Medical Oncology (ESMO) in Milan, Italy.

Albireo reports positive results from A3309 Phase IIb study in chronic idiopathic constipation

Albireo today announced positive top-line results from a Phase IIb study in chronic idiopathic constipation (CIC) assessing efficacy and safety of three different dose levels (5, 10 and 15 mg orally once a day) of the investigational drug A3309 during an eight week trial. Analyses of the data show clinically meaningful and statistically significant improvement [...]

Helix completes GLP toxicology study milestone in L-DOS47 development program

Helix BioPharma Corp. today announced that it has completed its definitive GLP, rodent and primate, repeat-dose toxicology studies with L-DOS47. These studies demonstrated a good safety profile in an expanded number of rodent and primate test animals, building upon Helix’s positive findings from its preliminary non-GLP toxicology studies.