(MedPage Today) — Lab rats who have diagnostic skills as well as possible new therapeutic target for Alzheimer’s disease research highlight this week’s edition of Lab Notes, a potpourri of research findings selected by the MedPage Today staff.
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Filed under: General Health News
WASHINGTON (MedPage Today) — The FDA’s decision to seek withdrawal of the breast cancer indication for bevacizumab (Avastin) came as no great surprise to many breast cancer experts.
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WASHINGTON (MedPage Today) — The FDA is warning against use of the injectable form of dolasetron mesylate (Anzemet) to prevent nausea and vomiting in patients undergoing cancer chemotherapy, as new data indicate the drug can cause life-threatening cardiac arrhythmias.
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Viron Therapeutics Inc. today announced that the results of Viron’s Phase 2a trial for VT-111 were published today in Circulation: Cardiovascular Interventions. In the study led by Dr. Jean-Claude Tardif, Director of the Research Centre at the Montreal Heart Institute, VT-111, also known as Serp-1, met both its primary and secondary endpoints of safety and [...]
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Catalyst Biosciences, Inc., the leading company in the discovery and development of engineered proteases, today announced the receipt of a $4.0 million milestone payment from Pfizer Inc. under the terms of the collaboration agreement for the development of improved recombinant human Factor VIIa variants for the treatment of hemophilia and other bleeding disorders.
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The Muscular Dystrophy Association today announced it has awarded $1.4 million in new research funding to the biopharmaceutical firm Repligen of Waltham, Mass., to complete the preclinical work needed to begin human clinical trials of a promising therapeutic compound for spinal muscular atrophy (SMA).
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NovImmune announced today, following its July 2010 deal with Genentech/Roche, that it obtained further financing of CHF 20 million. The series B financing round of CHF 20M was led by BZ Bank Aktiengesellschaft.
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Amarin Corporation plc (Nasdaq: AMRN), a clinical-stage biopharmaceutical company with a focus on cardiovascular disease, reported the completion of patient randomization for its ANCHOR trial, a pivotal Phase 3 trial of AMR101…
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AstraZeneca (NYSE: AZN) announced that the US Food and Drug Administration (FDA) has issued a complete response letter (CRL) for the New Drug Application (NDA) for ticagrelor (BRILINTA™). In the CRL, the FDA requested additional analyses of the PLATO data…
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Amira Pharmaceuticals, Inc. announced that it has successfully identified a novel pre-clinical candidate for its newest lysophosphatidic acid (LPA)-related program, autotaxin. Autotaxin is an enzyme upstream from LPA receptors and has been implicated in a number of diseases including rheumatoid arthritis, glioblastoma, lung, breast, ovarian and thyroid cancers…
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