More Aggressive Whooping Cough Vaccine Use Advised

Among other changes in recommendations, the AAP and the CDC have removed their previous minimum interval between administering a tetanus or diphtheria vaccine and the Tdap. Medscape Medical News

AAP Updates Polio Vaccine Recommendations

If a child is at imminent risk for exposure, with planned travel to certain countries, the AAP recommends that the IPV doses be administered at minimum ages and intervals. Medscape Medical News

AAP Updates Vaccine Recommendations (CME/CE)

(MedPage Today) — The American Academy of Pediatrics (AAP) has updated some of its vaccine guidance to harmonize recommendations with those of the Advisory Committee on Immunization Practices.

Smaller and faster clinical drug trials could improve gains in cancer survival

With the advent of personalised medicine, gains in cancer survival over the long term could be improved by running smaller, faster trials with less stringent evidence criteria, a researcher told the 2011 European Multidisciplinary Cancer Congress.

Pacira announces data from EXPAREL clinical study presented at ASPS 2011 meeting

Pacira Pharmaceuticals, Inc. today announced that the company’s lead investigational product for postsurgical pain management, EXPAREL, was highlighted in the “Hot Topics in Plastic Surgery” panel at the annual scientific assembly of the American Society of Plastic Surgeons (ASPS) in Denver, Colo.

Zoledronic acid may benefit post-menopausal women with breast cancer

A trial investigating the use of zoledronic acid to aid chemotherapy for breast cancer has found a significant benefit for post-menopausal women, according to results presented at the 2011 European Multidisciplinary Cancer Congress.

Long-term results from ARIAD’s ponatinib Phase 1 study on CML and Ph+ ALL

ARIAD Pharmaceuticals, Inc. today announced long-term results of the Phase 1 study of its investigational pan-BCR-ABL inhibitor, ponatinib, in heavily pretreated patients with resistant and refractory chronic myeloid leukemia (CML) and Philadelphia-positive acute lymphoblastic leukemia.

Positive interim data from Aeterna Zentaris’ AEZS-108 Phase 1/2 study on prostate cancer

Aeterna Zentaris Inc., today announced positive interim data for the Phase 1 portion of its ongoing Phase 1/2 study in castration and taxane-resistant prostate cancer with its targeted cytotoxic luteinizing hormone releasing hormone (LHRH) analog, AEZS-108.

JDRF, iCo Therapeutics collaborate for iCo-007 Phase 2 trial in DME

iCo Therapeutics Inc. today announced that the company has entered into a research collaboration agreement with JDRF, the worldwide leader for research to cure, treat, and prevent type 1 diabetes (T1D), to support the previously announced Phase 2 investigator sponsored clinical trial investigating iCo-007 in Diabetic Macular Edema.

Positive results from Clermont’s non-preserved latanoprost phase III trial on glaucoma

Clermont Pharmaceuticals, Inc., a privately held ophthalmic-focused biopharmaceutical company, announced today positive results from a phase III trial of non-preserved latanoprost. In the study, non-preserved latanoprost was compared to Xalatan (latanoprost ophthalmic solution) 0.005%, in subjects diagnosed with open-angle glaucoma.