AAP Backs HIV Tests for Teens (CME/CE)

(MedPage Today) — Pediatricians should offer routine HIV testing to adolescents at least once before they are 16 to 18 if the local prevalence of the virus is greater than 0.1%, according to a new policy statement from the American Academy of Pediatrics.

Teenage Girls Rate PID Worse Than Their Parents Do (CME/CE)

(MedPage Today) — Parents underestimate the impact of a diagnosis of pelvic inflammatory disease (PID) on their adolescent daughters, a survey suggested.

Diabetic Minorities Miss More PCP Visits (CME/CE)

(MedPage Today) — African-American and Latino patients with diabetes are more likely than whites to skip planned primary care appointments, a large cohort study found.

Uninsured Kids Unlikely to Get Asthma Diagnosis (CME/CE)

(MedPage Today) — Children with intermittent asthma symptoms are less likely to receive a formal diagnosis when they lack health insurance, but the same was not true for kids with persistent symptoms, researchers said.

Initiation of two IPI-145 Phase 1 clinical trials triggers $4M milestone payment to Intellikine

Intellikine, Inc., a company focused on the discovery and development of innovative, small molecule drugs targeting the PI3K/mTOR pathway, announced today that it has earned $4 million in milestone payments upon the initiation of two Phase 1 clinical trials of IPI-145.

Vegenics receives IND approval from FDA for VGX-100 Phase I study in late stage cancers

Circadian Technologies Limited announces that its 100% owned subsidiary, Vegenics Pty Ltd, has received approval for its investigational new drug application from the U.S. Food and Drug Administration to initiate clinical trials of VGX-100.

Infinity commences two IPI-145 Phase 1 clinical trials for hematologic malignancies

Infinity Pharmaceuticals, Inc. today announced that it has initiated two Phase 1 clinical trials of IPI-145, a potent, orally available inhibitor of phosphoinositide-3-kinase (PI3K) delta and gamma. These two enzymes are implicated in hematologic cancers as well as a broad range of inflammatory conditions, which are the areas of focus within Infinity’s PI3K clinical development [...]

Positive initial results from CytRx’s INNO-206 Phase 1b/2 clinical trial for advanced solid tumors

CytRx Corporation, a biopharmaceutical company specializing in oncology, today announced favorable response and safety indications from a group of patients with advanced solid tumors (principally soft tissue sarcomas) in the Company’s ongoing Phase 1b/2 clinical trial with INNO-206, its tumor-targeting conjugate of the commonly used chemotherapeutic agent doxorubicin.

YM BioSciences announces results of nimotuzumab Phase II study on DIPG

YM BioSciences Inc. today announced that preliminary results of a Phase II study evaluating the safety and efficacy of nimotuzumab in pediatric patients with recurrent diffuse intrinsic pontine glioma (DIPG) were reported at the 43rd Congress of the International Society of Paediatric Oncology (SIOP) conference being held in Auckland, New Zealand.

Fierce Vaccines highlights Inovio’s VGX-3100 as one of 10 Promising Therapeutic Vaccines

Inovio Pharmaceuticals, Inc., which is advancing synthetic vaccines to fight cancers and infectious diseases, announced today that VGX-3100, its investigational SynCon vaccine for treating cervical dysplasia and cancer caused by human papillomavirus, was highlighted by Fierce Vaccines as one of 10 Promising Therapeutic Vaccines.