FDA Staff Says Decitabine No Help in AML

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WASHINGTON (MedPage Today) — Decitabine (Dacogen), a hypomethylating agent, does not appear to improve mortality in older patients with acute myelogenous , FDA reviewers concluded.

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Fighters Need Padded Gear to Cut Head Injury (CME/CE)

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(MedPage Today) — Rotational head injuries in fighting sports can be minimized if participants wear padded boxing gloves and headgear rather lighter protective gear or no protection at all, a laboratory study suggested.

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FDA Issues Warning on Acid Reflux Drugs

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(MedPage Today) — The FDA warned today that use of proton pump inhibitors — including popular brands such as Nexium, Prilosec, and Prevacid — may increase the risk of Clostridium difficile-associated diarrhea.

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Bread, Bologna, Cheese Top List of Salty Foods

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(MedPage Today) — Just 10 types of food account for nearly half of the nation’s excessive sodium intake, government researchers found.

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Researchers examine effectiveness of Omega 3 in treating psychiatric symptoms

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Researchers at Zucker Hillside Hospital’s Recognition and Prevention (RAP) Program who have worked with teenagers at risk for serious illness for the past decade are now studying the effectiveness of Omega 3 fatty acids (fish oil) for treating psychiatric symptoms.

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Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1

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Genzyme, a Sanofi company, announced today four-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate.

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Exemestane has negative effect on postmenopausal women’s bone health

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Exemestane, a used in the prevention of breast in postmenopausal women, has a negative effect on bone density and structure in these women, despite calcium and vitamin D supplements.

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Center for LAM Research and Clinical Care at BWH to conduct phase I combination drug trial

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The Center for LAM Research and Clinical Care at Brigham and Women’s Hospital (BWH) has been awarded a $1 million plus, four-year grant from the U.S. Department of Defense Office of the Congressionally Directed Medical Research Programs to fund their work on lymphangioleiomyomatosis.

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Patients with degenerative spondylolisthesis do not benefit from epidural steroid injections

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Researchers at the Rothman Institute at Jefferson examined data on patients being treated for lumbar stenosis and the degenerative spine condition spondylolisthesis and found that patients who received epidural injections (ESI) had a higher rate of crossover to and fared worse in physical health and bodily pain versus those who did not receive ESI, dispelling their pre-study hypothesis.

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Antidepressants make patients feel less satisfied after THR

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Patients taking antidepressants up to three years prior to undergoing a total hip replacement (THR) were more likely to report greater pain before and after and less satisfaction with their procedure, according to new research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

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