Combination of Toca 511 and 5-FC may prolong survival in glioblastoma

Tocagen Inc. today announced the publication of data showing the company’s investigational treatment for high grade glioma eradicates brain tumors and provides a dramatic survival benefit in mouse models of glioblastoma.

Clazosentan reduces risk of blood vessel spasm in patients with brain aneurysm

An experimental drug, clazosentan, reduced the risk of blood vessel spasm in patients with a brain aneurysm, according to research presented at the American Stroke Association’s International Stroke Conference 2012.

Discovery May Lead To New Treatment For Rett Syndrome

Researchers at Oregon Health & Science University have discovered that a molecule critical to the development and plasticity of nerve cells - brain-derived neurotrophic factor (BDNF) - is severely lacking in brainstem neurons in mutations leading to Rett syndrome, a neurological developmental disorder…

FDA allows marketing of Stratify JCV Antibody ELISA test for PML

Today, the U.S. Food and Drug Administration allowed marketing of the first test to help determine the risk for a rare brain infection called progressive multifocal leukoencephalopathy (PML) in people using the drug Tysabri (natalizumab) to treat multiple sclerosis (MS) or Crohn’s disease.

Anabolic steroids do not appear to contribute to CTE

Anabolic steroids don’t appear to contribute to degenerative brain disease caused by repeated head trauma in athletes, according to a study in the January issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

More PML Cases Turn Up With Adcetris

(MedPage Today) — Two new cases of a life-threatening brain inflammation have been seen in patients treated with the lymphoma drug brentuximab vedotin (Adcetris), the FDA said.

Researchers discover a way to sensitize glioblastoma to chemotherapy

Brain cancer cells are particularly resistant to chemotherapy - toxins enter the cells, but before the toxins can kill, cancer cells quickly pump them back outside. In fact, brain cancer cells are even better than healthy cells at cleaning themselves. This means that when hit with chemotherapy, healthy cells tend to die before brain cancer [...]

Key Cannabis Components Have Opposite Effects on the Brain

The main psychoactive components of marijuana, THC and cannabidiol, have opposite effects on brain function. The first can induce psychosis, the second can have antipsychotic properties. Medscape Medical News

Wake Forest Baptist participates in novel brain tumor vaccine clinical trial

A national clinical trial testing the efficacy of a novel brain tumor vaccine has begun at Wake Forest Baptist Medical Center, the only facility in the Southeast to participate.

Marijuana ingredients appear to affect regional brain function during salience processing

Different ingredients in marijuana appear to affect regions of the brain differently during brain processing functions involving responses to certain visual stimuli and tasks, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals.