Exemestane has negative effect on postmenopausal women’s bone health

Exemestane, a drug used in the prevention of breast cancer in postmenopausal women, has a negative effect on bone density and structure in these women, despite calcium and vitamin D supplements.

Komen Official Quits After Controversy

(MedPage Today) — A vice-president at the Susan G. Komen for the Cure Foundation has resigned in the wake of the controversy surrounding the organization’s decision — since reversed — to stop funding Planned Parenthood’s breast cancer programs.

Roche’s new breast cancer drug Pertuzumab up for FDA review

U.S. health regulators, the Food and Drugs Administration (FDA) has granted a priority review for an experimental Roche breast cancer drug that in clinical trials added six months to the time before the disease worsened. Pertuzumab approval decision is due by June 8th this year. It could be used with Herceptin in HER2-positive patients. This [...]

Soy isoflavone supplements do not reduce breast cancer cell proliferation

Soy isoflavone supplements did not decrease breast cancer cell proliferation in a randomized clinical trial, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

Komen Reverses Planned Parenthood Funding Cut

(MedPage Today) — The Susan G. Komen for the Cure Foundation has reversed its decision to cut funding to Planned Parenthood for breast cancer screening and education.

Pertuzumab plus trastuzumab and docetaxel has advantages over current clinical gold-standard treatment

Roche/Genentech/Chugai’s pertuzumab plus trastuzumab (Roche/Genentech/Chugai’s Herceptin) and docetaxel (Sanofi’s Taxotere, generics) will become Decision Resources’ proprietary clinical gold-standard treatment for metastatic first-line HER2-positive breast cancer in 2015.

Dropping Planned Parenthood Is Not Political, Says Susan G. Komen For The Cure

Breast cancer charity, Susan G. Komen for the Cure, says that dropping Planned Parenthood from its granting process is not political, and says it is “dismayed and extremely disappointed” that its action has been mischaracterized. The charity says it has taken actions to make its granting process stronger and more effective, resulting in Planned Parenthood [...]

Anti-HER2 dendritic cell vaccine shows promise against DCIS

Researchers at the Perelman School of Medicine at the University of Pennsylvania report that a short course of vaccination with an anti-HER2 dendritic cell vaccine made partly from the patient’s own cells triggers a complete tumor eradication in nearly 20 percent of women with ductal carcinoma in situ (DCIS), an early breast cancer.

Link Between Parabens and Breast Cancer?

A new study has found traces of parabens in breast cancer tumors. Do they play a role in the development of cancer? Medscape Medical News

Studies Reignite Debate over Avastin in Breast Cancer (CME/CE)

(MedPage Today) — Women with HER2-negative metastatic breast cancer had significantly higher rates of pathologic complete response when bevacizumab was added to neoadjuvant chemotherapy, two large clinical trials showed.