FDA Panel Turns Down Bone Drug in Prostate Ca

WASHINGTON (MedPage Today) — An FDA panel has voted 12-1 against expanding the indication for Amgen’s denosumab (Xgeva) to prevent the spread of prostate cancer to the bones in men with a high-risk form of the disease.

Exemestane has negative effect on postmenopausal women’s bone health

Exemestane, a drug used in the prevention of breast cancer in postmenopausal women, has a negative effect on bone density and structure in these women, despite calcium and vitamin D supplements.

Fasting and chemotherapy drugs more effectively treat cancers

Man may not live by bread alone, but cancer in animals appears less resilient, according to a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.

Scientists study a botanical formula that kills aggressive prostate cancer tumors

Scientists at Indiana University, Methodist Research Institute study a botanical formula that kills aggressive prostate cancer tumors. Their findings, based on experiments in mice using a human prostate cancer tumor model, appear online in The International Journal of Oncology.

Ovarian Cancer Screening Common Despite Lack of Proof (CME/CE)

(MedPage Today) — More than 90% of primary care physicians reported ordering ovarian cancer screening tests not recommended for women with a low or average risk for the disease, a national survey showed.

Komen Official Quits After Controversy

(MedPage Today) — A vice-president at the Susan G. Komen for the Cure Foundation has resigned in the wake of the controversy surrounding the organization’s decision — since reversed — to stop funding Planned Parenthood’s breast cancer programs.

Benefit of Bone Drug in Prostate Cancer in Doubt

WASHINGTON (MedPage Today) — FDA reviewers have questioned whether expanding the indication for Amgen’s denosumab (Xgeva) to prevent the spread of prostate cancer to the bones would provide much added benefit.

Clinical Cancer Research publishes results of Aduro’s ANZ-100 and CRS-207 Phase 1 studies

Aduro BioTech, Inc. is pleased to announce the publication of two therapeutic cancer vaccine Phase 1 studies in Clinical Cancer Research. In the article, which was featured as one of the highlights of the issue, Dr. Dung Le et al. reported that intravenous administration of ANZ-100 and CRS-207 was well tolerated in subjects with advanced, [...]

Three new targeted drugs can lead to fatal cancer complications

Treatment with three relatively new “targeted” cancer drugs has been linked to a slightly elevated chance of fatal side effects, according to a new analysis led by scientists at Dana-Farber Cancer Institute. They added that the risk remains low, but should be taken into account by physicians and patients.

Roche’s new breast cancer drug Pertuzumab up for FDA review

U.S. health regulators, the Food and Drugs Administration (FDA) has granted a priority review for an experimental Roche breast cancer drug that in clinical trials added six months to the time before the disease worsened. Pertuzumab approval decision is due by June 8th this year. It could be used with Herceptin in HER2-positive patients. This [...]