WASHINGTON (MedPage Today) — An FDA panel has voted 12-1 against expanding the indication for Amgen’s denosumab (Xgeva) to prevent the spread of prostate cancer to the bones in men with a high-risk form of the disease.
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(MedPage Today) — The FDA warned today that use of proton pump inhibitors — including popular brands such as Nexium, Prilosec, and Prevacid — may increase the risk of Clostridium difficile-associated diarrhea.
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Exemestane, a drug used in the prevention of breast cancer in postmenopausal women, has a negative effect on bone density and structure in these women, despite calcium and vitamin D supplements.
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The Center for LAM Research and Clinical Care at Brigham and Women’s Hospital (BWH) has been awarded a $1 million plus, four-year grant from the U.S. Department of Defense Office of the Congressionally Directed Medical Research Programs to fund their work on lymphangioleiomyomatosis.
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Attention-deficit/hyperactivity disorder (ADHD) affects 5-9% of youth and is frequently treated with stimulant medications, such as methylphenidate and amphetamine products. A recent safety communication from the US Food and Drug Administration advised that all patients undergoing ADHD treatment be monitored for changes in heart rate or blood pressure.
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Man may not live by bread alone, but cancer in animals appears less resilient, according to a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.
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There is growing evidence that supports an association between atypical fractures of the femur- a rare break of the thigh bone, typically without trauma - and the use of bisphosphonates, drugs proven to enhance bone density and reduce fracture incidence caused by osteoporosis.
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A new study shows a rising number of drugs for infectious diseases that are in short supply, with serious consequences. Medscape Medical News
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(MedPage Today) — The investigational anticoagulant vorapaxar significantly reduced cardiovascular events, but at the expense of intracranial hemorrhage, according to top-line results announced today by drugmaker Merck.
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WASHINGTON (MedPage Today) — FDA reviewers have questioned whether expanding the indication for Amgen’s denosumab (Xgeva) to prevent the spread of prostate cancer to the bones would provide much added benefit.
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