Gilead Sciences seeks MAA in Europe for fixed-dose combination of Truvada and TMC278 for HIV-1 infection

Gilead Sciences, Inc. today announced that it has submitted a Marketing Authorization Application (MAA) to the European Medicines Agency (EMA) for marketing approval for the fixed-dose combination of Truvada® (emtricitabine and tenofovir disoproxil (as fumarate)) and Tibotec Pharmaceuticals’ investigational non-nucleoside reverse transcriptase inhibitor TMC278 (rilpivirine (as hydrochloride)) for the treatment of HIV-1 infection in adults.

Tibotec submits MAA for investigational HIV drug TMC278 to European Medicines Agency

Tibotec Pharmaceuticals today announced its submission of a Marketing Authorisation Application (MAA) to the European Medicines Agency (EMA) for TMC278 (rilpivirine, as hydrochloride), an investigational non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV. The proposed indication would make TMC278 available for once-daily use with other antiretroviral agents in treatment-naive HIV-1-infected adults.

Also In Global Health News: China’s First HIV Discrimination Case; Congo Mass Rape; S. Sudan Flooding; Kenya’s Population Growth; Family Planning

Court Accepts China’s First HIV Discrimination Case, State Media Reports “A municipal court in central China has accepted the country’s first lawsuit alleging work discrimination because of HIV status, state media reported Tuesday,” the Associated Press reports (8/31)…

To Reduce HIV Risk Among Men Who Have Sex With Men, Better Interventions Are Needed

Although a cognitive-behavioral intervention to encourage men who have sex with men to reduce their substance use and sexual risk behavior (as both are linked) was partially successful, a similar reduction was achieved in comparison groups who did not receive the intervention suggesting that better methods for changing behaviors are needed…

Also In Global Health News: U.N. Investigates DRC Rape Allegations; HIV Aid To Botswana; HIV Discrimination In Nigeria; Circumcision In Kenya; More

U.N. Sends Top Aides To Investigate Alleged Mass Rapes In DRC “The United Nations is investigating claims that rebel fighters raped more than 150 women and baby boys in the Democratic Republic of Congo,” the BBC reports. U.N. Secretary-General Ban Ki-moon is “sending two top aides” to the country and [...]

Also In Global Health News: Ebola Drug Study; Niger Hunger Crisis; WHO’s Breastfeeding Guidelines For HIV-Positive Mothers; Slowing India’s Birth Rate

Treatment Administered To Monkeys Within Hour Of Ebola Infection Found To Be 60% Effective, Study Finds “A treatment administered to rhesus monkeys within an hour of being infected by the deadliest strain of Ebola was 60 percent effective, and a companion drug was 100-percent effective in shielding cynomolgus monkeys against [...]

Combination of 2 FDA approved drugs eliminate HIV infection

Researchers at the University of Minnesota Academic Health Center have identified two drugs that, when combined, may serve as an effective treatment for HIV.

Bristol-Myers Squibb And ADAP Crisis Task Force Announce Enhanced, Multi-year Support For AIDS Drug Assistance Programs (ADAPs) In The United States

Bristol-Myers Squibb Company (NYSE: BMY) and the ADAP Crisis Task Force (ACTF) announced an enhanced agreement to support the efforts of AIDS Drug Assistance Programs (ADAPs) to provide antiretroviral medicines to people living with HIV and AIDS…

Also In Global Health News: AIDS Vaccine Testing; Misoprostol In Pakistan; Russian Wheat Exports; Generic Drugs In Uganda; Poverty In Egypt; More

Crucell And Harvard To Test Experimental AIDS Vaccine In Uninfected Adults The pharmaceutical company Crucell, in collaboration with Harvard University, “plans to test its experimental AIDS vaccine in the U.S. and in Africa, advancing the quest for a protective shot against” HIV, Bloomberg reports…

Bristol-Myers Squibb, ACTF announce enhanced agreement to support ADAPs

Bristol-Myers Squibb Company and the ADAP Crisis Task Force today announced an enhanced agreement to support the efforts of AIDS Drug Assistance Programs to provide antiretroviral medicines to people living with HIV and AIDS. Building on an agreement signed in March of 2010, today’s announcement marks a multi-year enhancement to assist ADAPs in meeting the [...]