FDA Panel Turns Down Bone Drug in Prostate Ca

WASHINGTON (MedPage Today) — An FDA panel has voted 12-1 against expanding the indication for Amgen’s denosumab (Xgeva) to prevent the spread of prostate cancer to the bones in men with a high-risk form of the disease.

Scientists study a botanical formula that kills aggressive prostate cancer tumors

Scientists at Indiana University, Methodist Research Institute study a botanical formula that kills aggressive prostate cancer tumors. Their findings, based on experiments in mice using a human prostate cancer tumor model, appear online in The International Journal of Oncology.

Benefit of Bone Drug in Prostate Cancer in Doubt

WASHINGTON (MedPage Today) — FDA reviewers have questioned whether expanding the indication for Amgen’s denosumab (Xgeva) to prevent the spread of prostate cancer to the bones would provide much added benefit.

Positive updated results from Aeterna Zentaris’ AEZS-108 Phase 1 trial on CRPC

Aeterna Zentaris Inc. today reported positive updated results for the Phase 1 portion of its ongoing Phase 1/2 study in castration- and taxane-resistant prostate cancer (CRPC) with AEZS-108 (zoptarelin doxorubicin), the Company’s targeted cytotoxic luteinizing hormone-releasing hormone (LHRH) analog.

Men With Reduced Fertility At Reduced Risk For Prostate Cancer

Involuntary childlessness owing to reduced fertility is a concern for many men. However, these men do have one advantage - they run a significantly lower risk of suffering from prostate cancer. Researchers are interested in whether this phenomenon could be used in the fight against cancer. There is a clear link between male subfertility and [...]

Proton Beam No Better than IMRT for Prostate Cancer (CME/CE)

SAN FRANCISCO (MedPage Today) — For localized prostate cancer, proton beam radiation offers no advantage in minimizing recurrences or side effects, study results suggested.

Preliminary results from CINJ’s Celebrex and Lipitor Phase II combination trial on prostrate cancer

Research from The Cancer Institute of New Jersey (CINJ) on the FDA-approved drugs Celebrex and Lipitor — used respectively for arthritis pain and lowering cholesterol — shows that these drugs are well tolerated in the treatment of recurrent prostate cancer.

Dutasteride delays prostate cancer progression in men

For men diagnosed with low-risk, localized prostate cancer, being treated with the drug dutasteride delays disease progression and initiating active treatment, and also reduces anxiety, show the results of a three-year international clinical trial led by Dr. Neil Fleshner, Head of the Division of Urology, University Health Network.

KSU professor turns to nutrition to tackle prostate cancer

A Kansas State University professor is turning to nutrition to tackle prostate cancer. Brian Lindshield, assistant professor of human nutrition, is helping men make more informed diet decisions by studying foods and dietary supplements that may reduce the risk of prostate cancer. Prostate cancer is one of the most common forms of cancer among men [...]

Animal study confirms dramatic effects of natural formula against prostate cancer

New animal study confirms the dramatic effects of a natural formula against aggressive prostate cancer tumors. Researchers at the Methodist Research Institute at Indiana University conducted the study on mice, using a human prostate cancer xenograft model.