Cabazitaxel with IMRT, androgen deprivation therapy may extend survival for prostate cancer patients

Jefferson’s Kimmel Cancer Center has started a Phase I clinical trial investigating the latest prostate cancer chemotherapy drug to extend survival, Cabazitaxel, in combination with radiation and hormone therapy. This first-of-its-kind multimodality approach could improve disease control and eventually survival for locally advanced prostate cancer patients.

Researchers create prostate cancer drug delivery system

Honing chemotherapy delivery to cancer cells is a challenge for many researchers. Getting the cancer cells to take the chemotherapy “bait” is a greater challenge. But perhaps such a challenge has not been met with greater success than by the nanotechnology research team of Omid Farokhzad, MD, Brigham and Women’s Hospital (BWH) Department of Anesthesiology [...]

Gone Astray: US Prostate Cancer Screening Trial

The controversial Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial has longer follow-up and more controversy. Medscape Medical News

FDA To Review Potential New Use Of XGEVA® (Denosumab) At Oncologic Drugs Advisory Committee Meeting

Amgen (NASDAQ: AMGN) announced the U.S. Food and Drug Administration (FDA) has invited the Company to participate in a meeting of the Oncologic Drugs Advisory Committee (ODAC) on Feb. 8, 2012 to discuss the supplemental Biologics License Application (sBLA) for XGEVA® (denosumab) to treat men with castration-resistant prostate cancer (CRPC) at high risk of developing [...]

FDA invites Amgen for ODAC meeting on XGEVA sBLA to treat castration-resistant prostate cancer

Amgen today announced the U.S. Food and Drug Administration has invited the Company to participate in a meeting of the Oncologic Drugs Advisory Committee (ODAC) on Feb. 8, 2012 to discuss the supplemental Biologics License Application (sBLA) for XGEVA (denosumab) to treat men with castration-resistant prostate cancer (CRPC) at high risk of developing bone metastases.

NIH Panel Backs Delayed Therapy for Prostate Cancer

(MedPage Today) — Active surveillance is a viable option that should be offered to low-risk patients, according to a draft statement issued by the panel.

Well-Done Red Meat May Increase Risk For Aggressive Prostate Cancer

New research led by the University of California, San Francisco (UCSF), offers further evidence of a link between aggressive prostate cancer and meat consumption, and suggests it is driven largely by consumption of grilled or barbecued red meat, especially when it is well-done…

Medicare to Pay for Infusing Provenge

(MedPage Today) — The Medicare and Medicaid programs will pay physician practices for the costs of infusing the prostate cancer vaccine sipuleucel-T (Provenge) as well as reimbursing for the drug itself, drugmaker Dendreon announced Monday.

Celgene to discontinue docetaxel and prednisone plus lenalidomide Phase III trial on CRPC

Celgene International Sàrl, a subsidiary of Celgene Corporation, announced that based on the recommendation from the Data Monitoring Committee (DMC) it will discontinue its pivotal double-blinded Phase III MAINSAIL trial that was designed to evaluate the efficacy and safety of docetaxel and prednisone with or without lenalidomide in patients with castrate-resistant prostate cancer.

Medicare to cover infusion costs for prostate cancer vaccine, company says

In Medicare news, the drug maker Dendreon says federal officials have said they will pay doctors to administer the drug. Also, policymakers are studying Medigap to see if curbs on those policies could help cut Medicare costs.